What Is the Difference Between Bio-PRF Lift® and Bio-CARE®
Bio-PRF Lift® and Bio-CARE® are signature protocols from CARE® Esthetics, both using platelet-rich fibrin (PRF) made from your own blood. The main difference is the laser. Bio-PRF Lift focuses on restoring volume and softening lines with PRF treatments alone, while Bio-CARE combines DEKA® CO2 laser therapy with PRF treatments to address texture, tone, and spots across the whole face.
Both protocols are offered through CARE® Esthetics at Bergen Oral & Maxillofacial Surgery’s Paramus, NJ office.
Key Takeaways:
- Bio-PRF Lift® and Bio-CARE® are both multi-step protocols that use PRF made from your own blood, with no synthetic fillers.
- Bio-PRF Lift combines microneedling with PRF, PRF injections, and natural Bio-Fillers® to restore volume and soften lines.
- Bio-CARE combines DEKA® laser therapy, including intra-oral lasering, under-eye lasering, and a laser peel, with PRF treatments to address texture, tone, and pigmentation across the whole face.
- Bio-CARE also includes complimentary removal of moles, veins, and age spots, when appropriate after evaluation.
- Amy Bhagat, RN, BSN – MSN-FNP-BC, provides both protocols at Bergen’s Paramus office under the guidance of board-certified surgeons.
What Bio-PRF Lift and Bio-CARE Have in Common
Both protocols are built on PRF, a concentrated portion of your own blood that contains platelets, growth factors, white blood cells, and fibrin. Your provider draws a small blood sample, processes it, and uses it to support your skin’s natural collagen production and healing. Because the material comes from your body, there are no synthetic gels or chemical fillers involved.
Two treatments appear in both protocols:
- Microneedling with PRF: A Dermapen® creates tiny channels in the skin, and PRF is applied so it can work beneath the surface to improve texture and firmness.
- Bio-Filler®: PRF is heat-processed into an injectable, all-natural filler that restores soft volume where your face needs it.
Learn more about Bio-Filler: The All-Natural Filler Alternative Made From Your Own PRF.
Bio-PRF Lift® vs. Bio-CARE® at a Glance
| Factor | Bio-PRF Lift® | Bio-CARE® |
|---|---|---|
| Steps included | Microneedling with PRF, PRF injections, Bio-Fillers® | Intra-oral lasering, under-eye lasering, laser peel, microneedling with PRF, Bio-Fillers® |
| Uses a laser | No | Yes, DEKA® laser technology |
| Main focus | Volume, lines, and facial contours | Texture, tone, pigmentation, and volume across the whole face |
| Extras | None | Complimentary removal of moles, veins, and age spots when appropriate after evaluation |
| Recovery | Minimal downtime | Minimal downtime, with redness that typically resolves within a few days |
What Is Bio-PRF Lift®?
Bio-PRF Lift is a 100% natural protocol designed to lift facial features, stimulate rejuvenation, and enhance volume and contours. It combines three PRF-based treatments in a single plan.
- Microneedling with PRF refreshes the skin’s surface.
- PRF injections deliver concentrated growth factors to improve texture, soften wrinkles, and support collagen.
- Natural Bio-Fillers® restore volume where it has faded.
The protocol is often used to address the appearance of under-eye hollows, nasolabial folds, lip lines, and cheeks or jowls that have started to look less firm.
Bio-PRF Lift supports a lifted-looking appearance, but it isn’t a substitute for surgery. If loose or sagging skin is your main concern, your provider can talk with you about what to expect and whether another approach would serve you better.
Who Bio-PRF Lift May Suit
Bio-PRF Lift tends to suit people whose main concern is lost volume and lines rather than skin texture or discoloration. It can also be a good option when laser treatment isn’t ideal. Darker skin tones and recent tans, for example, can raise the risk of pigment changes with some laser treatments, so your provider may recommend a PRF-only approach.
What Is Bio-CARE®?
Bio-CARE is the most advanced regenerative protocol offered through CARE Esthetics. It combines laser therapy with PRF treatments to activate collagen, smooth the skin, restore volume, and rejuvenate the entire face.
A Bio-CARE session brings together five treatments:
- Intra-oral lasering: The DEKA® CO2 laser works from inside the mouth to stimulate deep collagen production, which can improve the look of nasolabial folds, marionette lines, and facial laxity.
- Under-eye lasering: Laser resurfacing can help soften wrinkles, tighten under-eye skin, and refine contours without injections.
- Laser peel: A tailored laser peel targets the appearance of pigmentation, rough texture, fine lines, and visible pores.
- Microneedling with PRF: Supports collagen and smoother texture.
- Bio-Fillers®: Restore volume where your plan calls for it.
As a final step, Bio-CARE includes complimentary removal of moles, veins, and age spots.
Read more about What a CO2 Laser Is and What It Treats.
Who Bio-CARE May Suit
Bio-CARE is a strong fit for people who want to address several concerns in one protocol. If you’re noticing sun damage, uneven tone, dark spots, acne scars, or enlarged pores on top of volume loss and lines, the laser components target these concerns more directly.
How to Choose Between Bio-PRF Lift and Bio-CARE
Your main concern is the best starting point. If your main concerns are hollows under the eyes, deepening smile lines, or a face that looks thinner than it once did, Bio-PRF Lift is often the better starting point. If rough texture, discoloration, spots, and visible pores are the bigger issue, especially alongside volume loss, Bio-CARE may be the better fit.
Skin type and history matter too. Your provider will consider your skin tone, any history of cold sores, recent acne medications like isotretinoin, and how your skin has healed in the past before recommending a laser-based protocol.
During your free consultation, your provider reviews your skin, health history, and goals, then recommends the protocol or individual treatments that fit best. Some patients start with one of our individual CARE Esthetics treatments, like microneedling with PRF, before committing to a full protocol.
What Recovery Looks Like
Both protocols are minimally invasive, and most patients return to their routines quickly.
After Bio-PRF Lift, you may notice mild swelling, tenderness, redness, or bruising where microneedling and injections were done. These typically settle within a few days. Because PRF and Bio-Filler work with your body’s own repair process, improvements continue to develop over the following weeks.
After Bio-CARE, facial redness is normal and typically resolves within a few days. Your provider will give you a timeline based on your treatment settings. Collagen-related improvements continue to build over the following weeks.
Learn more about What to Expect After PRF, Microneedling, or Laser Treatments.
Why Choose CARE® Esthetics at Bergen Oral & Maxillofacial Surgery
Bergen has served North Jersey as a doctor-owned oral and maxillofacial surgery practice for over seven decades, and CARE Esthetics brings that same clinical standard to facial rejuvenation.
- Oversight from facial surgeons: Board-certified oral and maxillofacial surgeons, specialists in the structures of the face and jaw, guide the CARE Esthetics program.
- Advanced-practice care: Your protocol is administered by Amy Bhagat, RN, BSN – MSN-FNP-BC, a family nurse practitioner trained in PRF therapies, laser treatments, microneedling, and injectables.
- Trusted laser technology: Laser steps use DEKA® systems, backed by more than 40 years of laser innovation.
- A plan built for your face: Each treatment plan is customized to your facial structure, skin type, and goals.
- Easy to reach: CARE Esthetics is located in our Paramus office, a short drive for patients throughout North Jersey and Rockland County, NY.
Find Your Best Fit at a Free Consultation
Bio-PRF Lift and Bio-CARE both offer a natural way to refresh your appearance using your body’s own healing ability. The right choice depends on your skin, your concerns, and the results you want. Book your free consultation online or call or text (201) 477-2667.
Doctor-Owned. Doctor-Directed. Patient-Centered Care You Can Trust.
Bio-PRF Lift and Bio-CARE FAQs
Is Bio-CARE better than Bio-PRF lift?
Neither is better overall. Bio-CARE covers more concerns because it adds laser therapy, but Bio-PRF Lift may be the better fit if volume and lines are your main focus or if laser treatment isn’t right for your skin.
Can I start with one protocol and try the other later?
Possibly. Your provider can talk with you about sequencing treatments over time based on how your skin responds and what you’d like to address next.
Can I combine these protocols with BOTOX® Cosmetic?
Many patients do. PRF and laser treatments improve skin quality and volume, while BOTOX® Cosmetic relaxes the muscles behind expression lines.
How long do results last?
Results vary by person and protocol. PRF-based results develop gradually and can last for months, and laser improvements to texture and tone can last longer with good sun protection and skin care.
Are these treatments painful?
Most patients find both protocols well tolerated. Numbing cream is typically used to keep you comfortable, and laser steps usually feel warm or prickly.





